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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZEB1 All Species: 14.55
Human Site: S521 Identified Species: 32
UniProt: P37275 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P37275 NP_110378.3 1124 124074 S521 V K S E K D K S F E G G V N D
Chimpanzee Pan troglodytes XP_001157902 1209 135801 I567 L V T D D K M I E N H N I S T
Rhesus Macaque Macaca mulatta XP_001089463 1259 138826 S531 V K S E K D K S F E G G V N D
Dog Lupus familis XP_849865 1125 124104 N522 V K S E K D K N F E G G V N D
Cat Felis silvestris
Mouse Mus musculus Q64318 1117 122446 S501 V K S E T D K S F E G A R D D
Rat Rattus norvegicus Q62947 1109 121608 S501 V K S E K D K S F D G A A D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516149 1015 111872 N465 L K A Y Y A M N M E P N S D E
Chicken Gallus gallus P36197 1114 123132 N521 V K S E K D K N F E G E T N D
Frog Xenopus laevis NP_001085962 1093 120170 D522 L T I K T E K D T K F T E E S
Zebra Danio Brachydanio rerio NP_571784 1078 117826 G471 S N T E V C K G Q K L P E D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799337 1363 150632 S731 L A Q H K N E S D N H E I D D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.6 86.7 94.6 N.A. 86.5 86.1 N.A. 26 85.3 74.9 57 N.A. N.A. N.A. N.A. 21.7
Protein Similarity: 100 59.7 87.6 97.2 N.A. 91 90.9 N.A. 40.7 90.5 82.6 68.9 N.A. N.A. N.A. N.A. 38.5
P-Site Identity: 100 0 100 93.3 N.A. 73.3 66.6 N.A. 13.3 80 6.6 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 33.3 100 100 N.A. 80 86.6 N.A. 46.6 86.6 33.3 33.3 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 10 0 0 0 0 0 19 10 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 10 55 0 10 10 10 0 0 0 46 55 % D
% Glu: 0 0 0 64 0 10 10 0 10 55 0 19 19 10 19 % E
% Phe: 0 0 0 0 0 0 0 0 55 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 55 28 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 19 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 10 0 0 0 0 19 0 0 % I
% Lys: 0 64 0 10 55 10 73 0 0 19 0 0 0 0 0 % K
% Leu: 37 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % L
% Met: 0 0 0 0 0 0 19 0 10 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 10 0 28 0 19 0 19 0 37 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 10 0 55 0 0 0 0 46 0 0 0 0 10 10 10 % S
% Thr: 0 10 19 0 19 0 0 0 10 0 0 10 10 0 10 % T
% Val: 55 10 0 0 10 0 0 0 0 0 0 0 28 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _